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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca93b2e4ff11ae9acae6b14e6cfa8461a7761500e34877f202e0af42380e4cf' 
  AND token = 'lZglv73+pa9mL1vE5prXskCByiWaiB+gmXuEYl4M5dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}