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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c06f8acc1186fe7cc71a578ceeecd99dddb79048b38f2021793c7c5d2023268' 
  AND token = 'rl85O2Sow+jLN1KhL58fNUUnUg/cvIbRvdCMEo39nWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}