SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b211a2d74fd151c09352f1b2b9b4d004e229890e77925e64c9af33e2139d739' 
  AND token = 'QciLiUHxMDA8RicpCyKcoFIDxYzXSN6yRqnh4OT5oiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}