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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06351598cec96e4cdff79928a95580a8e22b6eac294700f7ad6c6be2a9326911' 
  AND token = '3Md8UXA/Oa+z5/hT9tkROv5y5uTOk1v1G8hTJgguYis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}