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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '617321083c747167ce8ce6b0e0942e415c8fcf2a2ade690642dfb89027f04d4a' 
  AND token = 'nrl4AtW6YQS0pEnDsODiEN6siQt1qvDJvjXTpl8x16g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}