SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e5c68a64ebfe662dd3d8a6389e19b3bf6b5eca2397247d7ea325b88e721bec' 
  AND token = 'oDTCoDMpO2fsF+J+bPSVbhOF5k829VP2hmpfAS32FBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}