SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39c943bd8c93a1e5201c0918f0d5c4c15bf7679c45ec2c79f790821fc2c1dae1' 
  AND token = 'rOdvKEjI9q50dEHEyhlwp4aqUGbJuG8NE7y9irYeoa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}