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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '541f858df0f18f0ca25ec1f615019a1f961dcad2e2de18f46c5485f7b48ae005' 
  AND token = 'HRNEhFxOAbq0p0pc+mZosjBg8u3u7yKI7gYL+yqyTvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}