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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b95bae948610521084ee1c3e22ebe89d1f166791b78905eeb4cd0135e9925ef' 
  AND token = 'HHwrRy1NZve2WTCm+cXEZSweKWvKsb8TFaD7/Y0igq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}