SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a800731b6c4aeb0ee73d04164aecb1bbcdda0148e6a4b59e2ff6c7b37536fc7' 
  AND token = 'E1o/6YzP+2LYQtz3cXwq+ej2FnaVmKf5/OTELVjX3vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}