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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d56c9cc22bebbba5191ed2c311efcba109f9f127e3a352c6a9e574f3309624' 
  AND token = 'MnLKrbFLm5vS1T7VgWq//7c/7nOqKDFw0pbEh+tNJAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}