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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf45fd3bb27e18594b1f64c91e8cffbfc0cb320bfa8adf6477cfed653789c720' 
  AND token = 'QkHAJNOb5w4+PsZWSNbkitPNJby0G/G5rZ5P8WcWZIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}