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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738a6ba3ef5dfee29e7ee3a7e9a6253d0be630e9757cc1bd58e93bc298049c94' 
  AND token = 'lBdd/LwaJ7gIAkzxgdVdl+IKUbbIIYLJcsJ62sgA4T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}