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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d9c879f36079e77ab803acaecb5023711c30ddefced00abca09ad049b586d1' 
  AND token = 'sTWwr21f2c+fT4R4AheePrUwvcLFVhRrdiY0P3CM4FA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}