SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd54293ec72639f09edaf780bda2981234d61bd272e322b628b9f88932fef626' 
  AND token = 'orYWBsH41cmg16dlXQSX3i4TWvhOoZ4T/HmNgsKwA6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}