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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb43d2224c48cdd19f3978c12dcad90fd84f18b51b99f7d84c3a43fb33e82e0' 
  AND token = 'hhP2qM+S50AOwNTw4L9yIsrMrnr5gBUp8qLQ7W+q6f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}