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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d75bebe2a6ee85fadc4252ad44ef60d21a181ffee5c624d184cf4a968d716ae' 
  AND token = 'qOZxEU1aRPRhUzA884+XL7icbZckgg8jylbxVK5fcpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}