SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c396aa55a5e8e26282ce1b1f12257289a5e4309bb7c6b7ed187838e23f3eaae3' 
  AND token = 'M6R1wko68q1YY8g6v244AlNt04LBuqbRCRNRwI90ZX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}