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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c77c742021686bb0692c8c0b7e6eb49226f6f91181512c29f9485e18720cdc6' 
  AND token = 'WbJf22u9LTiTcSfxXW3OPRZTYZsjUJVbAm21ckAEDUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}