SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758fa7f1d9e5b65acf2028470b1b2e4fec43dcbf9b11b3804d4515c18bd118fd' 
  AND token = 'JzkWgYKvIe8hmmsHZrFmesCDboLp/9XTbdhXe5NQicE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}