SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f315b6bdcdfe5f176af37cc85d11d22a1593e21c07be9c4d372a4091b4b69585' 
  AND token = 'aL4uh8N1lLHF+Qj/R1FISCxXn7nrYmLpMvSBP7CofA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}