SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f38fd074b597406c61111c1b165ed1fcd49809337054b447acc776595f03c36' 
  AND token = '3kycGEjDelFpA0l9AcTIeyC171W5DJVgE5CrTWZvNL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}