SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ab60fde9fb543066879d7eb2bf8fa92f1d9142395a07d8b7a8893552df315b0' 
  AND token = 'pPeYLo2dc0X/vLdS9JFEX+geFTg6LtBxTCsTtu66Jjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}