SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888a5561f38870cd0c413602c63dfda3e71b0f588a12101dbca7986a4b1a1b77' 
  AND token = '6zY/7+apCe99j0dpQSEKUUhM+AB5aX78dUq1efy4A40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}