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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20bc9a4bf92572c9c7f844b6506f3299e9c36816fa278987bbcb7f56500e7887' 
  AND token = 'bY1UMwkkoZeths4hYs2SzqSGw7JPwme98xynJuDGFXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}