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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '118b1d2421e8014e6712613aecca96eaffb64f88c4104a5f623fa6109f337c77' 
  AND token = '9Q5SElP8mWLjKJDOolRyAAw39W1Etl8e5oBI9s/9VfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}