SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9f43ad917ca51d516e4d718f8ec946849bca1b271bf4a4e08ceb959ddc7b81c' 
  AND token = 'Yk+sMfZ1eQib+MuVgFSSb2YoEIl4j+AwrOObmhIOszo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}