SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181259b082230c37a348d3aa846bd89be206fafae393bb537f74830cdab31a15' 
  AND token = 'E6Xmc5Yzjp363uxdNW3vUwGbBzV9A+J95Tt025+ZV/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}