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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd8b12c98acb26330d0f988800174152a8ad4988d0e11eb90644a7380e57d0f6' 
  AND token = 'BM58N2wwCc+stXlCo3cN0CG2iqP1l6TQ7E+UuQh6EsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}