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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00e39daedd002e2bc7863949fbc4cfc2e40ec85bf19b71baed3168e88bdf2d3' 
  AND token = '3axWj0tn+L1kN3a2kpFq88xDFDoI+9ehmlrb3Z5gIj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}