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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8256df21d0a56c081f5c18cb4557b2269acb87347c80a6aaf844e367d88d1f21' 
  AND token = 'f7um67xEfif0WQdIHCdfEFFTezs7BqX+y6EQ7VLtj5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}