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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42232a8896563ca008c1d4a74265a677a50a861a1373feb4fc852df7e9316a18' 
  AND token = 'qds0iu2/j1qCNbPRZl8r3WOrBHeNbpF3YSPgU9oB6xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}