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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a374508059a2ee0bab2ca0013b0e48343cf8fae0a7da5099588bbf58fbdb8186' 
  AND token = 'Y50gZqA/xOzOxxU2HgB5HjM5vj9nfyXfSQnZuPRpx4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}