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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28243e45a6795c1b183b92d66d453adbfad64f2dca9156145750572838b7d45a' 
  AND token = '/DO3brdFngYWxj/yVtMAqIeKa+dYsgY+WPo50ImEF3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}