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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7152ec07fbd8d42ed4466c8dbfa9b42e62ec194aaed3f8ab6a481f8297c2ae64' 
  AND token = 'r6kQrfVNIaYiXbBzVtL5U8xMBPvfTr4+xU3YG8NNWII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}