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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b9ee49ebda2333d1f5fe73bd0be36ad2854105d2316ee86d0179dff95648679' 
  AND token = 'w7U7oDT+5S8UHeYUtFfqk/PxzbMO/WFrYgl0Yza8HDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}