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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0130adedf14c18d45d8cfc13c2cafe467d2852a5acf71c3679e6e68debc17bb8' 
  AND token = 'KRpic9MUfP+h/83hVxbekCl8RoyybGx7QxK2mIni1KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}