SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c02a1510344624016a908799c04406c042a2ecc5f14444b8d210e7977624515d' 
  AND token = 'huNwWzyGdQntoKDJ7Gu7sBJbNIpl7HKDXghgXUPijws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}