SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0e01a080e265251b9c5490d2c796a2224a6c66469d5781aacf0ec54fa1e7fee' 
  AND token = 'va3zYc+y9g4i0k4qdIuwqrfEkX0y8Yt9cMVgFG6gwx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}