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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5597c3b0c49ec8a8c1c9463f4bacd4f7ad8e4b7577eb5a950e553d0a17dba28f' 
  AND token = 'GrEejeszoojrx1dVvHa2C9XeOPSh3iPsyXas62vL0Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}