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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee9152e7be3564f65d19fbfc0b168ce7af2447c313117ef9a4702b0aed38ac4' 
  AND token = 'HoHg3mR5x4iui2c1gsWH2lcxr5uR1Q7Rj2FLWMhqo0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}