SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b291b1cbaecbd2c4b192eaa027798b12f371e25b7f458b0572ee881806a94621' 
  AND token = 'n47zPSh53sG9hnsiPIiu3A7xQB1ExkwjS/ZGzAYRFd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}