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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af2a7d20ed8c319042cee696ed397ad8e38f9c851e50d1d85b496995ddee7ed' 
  AND token = 'ePI7C3ocpoflGYvbV1qHGhywyo6JEZ+8+uuEk7lYJR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}