SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6da327ea96ee888f77365415e7a47d68be3b5584cdec075e56fef9cc63f6ef' 
  AND token = '+g5XmE9SEtviwzqVKkPHL5R9UDl8LuwkiWNQgkU2pHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}