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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d929e1b7e45c60d76fa5f796abf6bd5def113848b5ea0ca71c4567fe91728a5' 
  AND token = 'pe1ypGw6yPpxoYk1nQDnY0SH4AdqgbV+/HT/Po++Keo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}