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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9556e0fb2fec872311753a17d8991992a8b1e89370a1bcb2ae5ea2d87de12872' 
  AND token = 'Ed7BS3aVGIIG86Pp8WL2f/FaiK2poIx685MA5dHOBhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}