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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a77b7aee8132f7384b4852687583562f22dd77210b6aeda20578fd50d221c04f' 
  AND token = 'WN1t3Vp2JMpYptG2uNCwCwK9/4E7cVa6RpMYzJqcFhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}