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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3447b3dba6c34d793c0a6b1473f7f04339c8e89da06d21b949f60680f16adc6' 
  AND token = 'rfOlfvMAwnsmedUqySuhYnrUcELpHbZPvS8e7iM8LPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}