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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee97cba1243ba153a87638de01a8f9a64ebb51583289509b045f9da7d79f491' 
  AND token = '1cFLMOJUtk8j1qTOS6f+s+Nx6lGXvy9YMAWDc/Bpovk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}