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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb647b4809f219fd392d912c3e9505e7ef465d8c74347105f2e8ca1f01005065' 
  AND token = 'G9Aqtf1xclqdqc/c49MdXUpVRsyw2aiH6OQjKJmOcl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}